The Uzumaki and Senju clans, being distant relatives, always had close ties. Mito ended up marrying Hashirama Senju, who would help found Konohagakure and became the village's First Hokage.[1]
During her husband's battle against Madara Uchiha at the Valley of the End, Hashirama at some point gained control of Kurama.
To gain power for Hashirama, Mito used a fūinjutsu to seal Kurama
within herself, becoming the beast's first jinchūriki. Despite the
seal's strength, it almost broke at some later point when she was going
through childbirth.[2] Eventually, her husband died in war, and Mito was left a widow.
Towards the final years of her life, it was decided that a new host for Kurama would have to be found. Kushina Uzumaki, one of Mito's clansmen, was then selected for the role due to her special chakra,
and was terrified by the idea. Mito comforted her however, and before
the transfer was performed, told Kushina that love was the only way to
counter Kurama's hatred.
Mito had long, bright-red hair and large, pupiless eyes. She wore an elaborate, high-collared kimono with the Uzushiogakure symbol on the back of the obi tied around her waist. Her hair was arranged in buns with hair pins
in them and three clips in the front. She also wore a dark shade of
lipstick and had a diamond mark on her forehead, similar to that of her
granddaughter Tsunade.
She also wore what appeared to be seal tags in her hair decals. In her
old age, her hair had grown much longer some of which she allowed to
hang into her back and — as the anime showed — became dark brown in
colour. She however maintained the two buns in her hair and wore a
simple loose fitting kimono held closed by a simple dark-coloured obi.
Not much is known about her fighting skills, but Kushina hailed her as a powerful kunoichi. She was shown to be exceptional at fūinjutsu, being able to seal the entirety of the Nine-Tailed Demon Fox
within herself. Also, due to being a member of the Uzumaki clan, Mito
had an exceptionally long life. Like Naruto, Mito also had the ability
to sense negative emotions due to her control over the beast.[3]
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